I never agree to allow all Google Cookies, and at the same time it is quite annoying to every first time after opening a browser have to click Customise > Search customization: Off > YouTube History: Off > Ad personalization: Off, before I can scroll down and click Confirm.

I use Cookie to automatically clear tracking cookies, cache, history etc when the browser is closed.

Is there a way I can use Cookie to remember the 3 google choices even after Cookie has cleaned?
And if so, would there be any negative consequences from this?

Super, Russell. Deleting the ~Library/Containers/Cookie folder was the solution. Thank you.

After I updated to macOS 12, I do not manage to get Cookie to clear my browsers on browser quit, as it is set to do in the preferences.

I did a clean installation when I upgraded to Monterey. Is there anything I can do to fix the issue?

Thank you.