I'm unsure why but all now working correctly.
Probably of no help but should anyone else have a similar problem, this is what I did following above post:
- Ran CleanMyMac X then re-booted Mac - no change, Cookie still not opening at login
- Ran CleanMyMac X to uninstall Cookie
- Ran CleanMyMac X for a third time and did a full system scan
- Re-booted Mac, downloaded and re-installed Cookie, entered licence details, selected Open at Login and received system message confirming Cookie opening at Login
- Updated to the Beta version 7.4.3.1
- Confirmed Cookie now appears in System Settings/Login Items and Extensions
- Re-booted Mac and Cookie opened at login
Maybe put this down to "...one of those things?" but whatever, thanks for suggestions and advice, much appreciated.