Also, how are you verifying that WiFiSpoof isn't working
Does WiFiSpoof show your newly selected address in its main window, after pressing either the Update or Randomize button?
I have. Using Safari Develop(er) mode, I can invoke Empty Caches and observe caches (such as pictured above), visible in Activity Monitor, get flushed.
Meaning, no Safari caches remain per Activity Monitor.
Ive just released v7.4.2 with some improvements to CMYK colors. But Apple doesn't have many inbuilt CMYK color profiles, so it still doesn't match the Adobe, or Affinity values you posted